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Description medications: Gestonoronkaproat (Gestonoroncaproat)

GESTONORONKAPROAT (Gestonoroncaproat). 17- a - Hydroxy-19-nor-pregna-4, 3, 20-dione-17-hexanoate (capronate) or 17- a-hydroxy-19-norprogesterone creates (capronate).

Synonyms: Depostat, Depostat, Gestronolhexanoat, Primostat and others.

White or creamy-white crystalline powder. It is soluble in water, soluble in alcohol.

On chemical structure is very close to oksiprogesterona kapronat and has a long-acting progestin activity.

The drug is used in prostate cancer, especially in patients with contraindications to surgery. Furthermore, the drug is used in cancer (carcinoma), endometrial and breast cancer.

It is believed that the mechanism of action of the drug at an adenoma is associated with inhibition at the cellular level, the stimulating effect of testosterone metabolites on tumor development.

Enter intramuscularly 200 mg 1 time per week. In the treatment of men recommended 2 - 3-month course at the resumption of symptoms, repeat the treatment. Women injected drug long.

In applying the drug in men may develop gynecomastia, violation of potency.

In some cases, immediately after the intramuscular injection may be short-term shortness of breath.

The drug should be used with caution in patients with chronic liver disease, and in patients with diabetes mellitus (monitor liver function and metabolism of carbohydrates). Caution should be exercised in bronchial asthma, epilepsy, migraine.

In the treatment of adenomas need to monitor renal function.

Product: 10% solution in oil (with addition of benzyl benzoate) in ampoules of 2 ml (200 mg per vial) in a package of five vials. Before introducing the solution was heated in a vial to body temperature.