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Description medications: Hloditan (Chloditanum)

HLODITAN (Chloditanum). 1- (o-chlorophenyl) -1- (p-chlorophenyl) -2, 2-dichloroethane.

Synonyms: Chlordithane, Lysodren, Mitothan, p -DDD.

A white crystalline powder, odorless. Practically insoluble in water, soluble in alcohol.

The drug is an inhibitor of the function of the adrenal cortex: inhibits the secretion of corticosteroids, can cause destructive changes, normal and tumor tissue of the adrenal cortex.

Used if necessary suppress excess glucocorticoid secretion at pituitary - Cushing (in combination with surgery or without it) with inoperable tumors of the adrenal cortex (corticosteroma) accompanied by increased formation of corticosteroids, as well as after surgical removal kortikosterom at elevated glucocorticoid levels in the body .

Ppimenyayut well as ppofilakticheskogo means after removal kortikosterom, in the absence of visible metastases and the continuing high level of glucocorticoids in the body.

Assign the inside, starting from 2 - 3 g per day for the first 2 - 3 days, then at a rate of 0.1 g / kg per day. The daily dose given 3 doses at 15 - 20 minutes after eating.

Treatment is performed under the control of the content of corticosteroids in the blood or urine; determination is made not less than 1 time in 10 - 14 days. Average course dose of 200 - 300, after receiving every 80 - 100 g are allowed a break 2 - 3 days. The total dose for the course and duration of treatment, specify in the course of treatment depending on the effectiveness and tolerability of the drug.

When using hloditana nausea, loss of appetite, headache, somnolence.

If necessary, reduce the dose or cancel the drug. recommended intake of vitamins to improve tolerability.

Product: 0.5 grams of pills in a package of 100 pieces.

Storage: Keep in a dry, dark place.