Description of the medicine: Aminoglutethimide (Aminoglutethimide)
AMINOGLUTETIMID (Aminoglutethimide). 3-Ethyl-3- (para-aminophenyl) 2, 6-dioxopiperidine.
Synonyms: Mamomit, Orimetin, Сutadren, Elipten, Mamomit, Оrimeten.
The chemical structure of aminoglutethimide is similar to the hypnotic and anticonvulsant drug glutetimide (synonyms: Noxiron - Nokhuron, Doriden-Doriden). It differs only in the presence of an amino group in the phenyl core.
Aminoglutethimide also has anticonvulsant activity, but it attracted the greatest interest as an inhibitor of the synthesis of adrenocorticosteroids, primarily hydrocortisone. It also inhibits estrogen biosynthesis.
Aminoglutethimide is used for Itsenko-Cushing's syndrome and for <pharmacological adrenalectomy> for tumors of the adrenal cortex (see Chloditan). Also used for breast cancer.
Assign inside 0.25 g 2 to 4 times a day. Take daily for a long time (depending on the course of the disease).
The drug is usually well tolerated. Allergic skin reactions, Quincke's edema are sometimes observed.
Release form: tablets on 0,25 g.