Medication Description: Bilignost (Billignostum)
Bis- (2, 4, 6-triyod-3-carboxyanilide) - adipic acid.
Synonyms: Adipiodine, Biligrafin, Cholografin, Cholospect, Endografin, Intrabilix, Iodipamide, Jodipamide, Radioselectan, Sodium iodipamide.
White or almost white fine-crystalline powder, slightly bitter taste. Practically insoluble in water and alcohol. Easily soluble in solutions of caustic alkalis. Contains about 65% iodine.
Available in the form of a 50% solution of methyl glucamine salt (Solutio Bilignosti 5% of injectionibus).
Synonyms of methyl glucamine salt: Ultrabil, Holambrin, Ultrabil, Cholambrin.
Clear yellowish liquid; pH 7, 0 - 8, 0.
Used for x-ray examination of the biliary tract and gallbladder.
For the study, 20 ml of a solution heated to body temperature is injected into a vein for 4-5 minutes. After 20-25 minutes, you can get an image of the bile ducts, and after 2-2.5 hours - an image of the gallbladder. Children are given 0.5 to 0.75 ml / kg.
Before the test, a tolerance test is carried out by injecting 1 - 2 ml of solution into a vein.
The drug is usually well tolerated. In some cases, dizziness, chills, nausea, vomiting, low blood pressure may appear. These phenomena usually pass on their own; if necessary, prescribe inhalation of oxygen and the introduction under the skin of 1 ml of 5% solution of ephedrine. If in the past the patient had allergic reactions, it is advisable to give him diphenhydramine or another anti-histamine drug within a few days before the introduction of bilignostus.
Contraindications to use are obstructive jaundice, acute diseases of the liver and kidneys, cardiac decompensation, pronounced forms of Graves' disease.
Product: in 20 ml ampoules.
Storage: in a cool, dark place.
When storing bilignost solutions, precipitation of crystals or crystallization of the contents of the ampoule is possible. In these cases, the ampoule is heated in a water bath. If the crystals completely disappear and the solution becomes transparent, and when cooled to 36 - 38 ° C, the crystals will not fall out again, the solution is suitable for use.