Description of the medicine: Bilignostum (Billignostum)
Bis (2, 4, 6-triiod-3-carboxyanilide) - adipic acid.
Synonyms: Adipiodine, Biligrafin, Cholografin, Cholospect, Endografin, Intrabilix, Iodipamide, Jodipamide, Radioselectan, Sodium iodipamide.
White or almost white fine crystalline powder, slightly bitter taste. Practically insoluble in water and alcohol. Easily soluble in caustic alkali solutions. Contains about 65% iodine.
Available in the form of a 50% solution of methylglucamine salt (Solutio Bilignosti 5% PPO injectionibus).
Synonyms of methylglucamine salt: Ultrabil, Holambrine, Ultrabil, Cholambrin.
Transparent yellowish liquid; pH 7.0-8.0.
Used for x-ray examination of the biliary tract and gall bladder.
For research, 20 ml of a solution warmed up to body temperature is injected into a vein for 4 - 5 min. After 20 - 25 minutes, you can get an image of the bile ducts, and after 2 - 2, 5 hours - the image of the gallbladder. Children are injected with 0.5 - 0.75 ml / kg.
Before the test, a tolerance test is performed by injecting 1 - 2 ml of solution into a vein.
The drug is usually well tolerated. In some cases, dizziness, chills, nausea, vomiting, and blood pressure may decrease. These phenomena usually pass on their own; if necessary, prescribe inhalation of oxygen and the introduction of 1 ml of a 5% solution of ephedrine under the skin. If in the past the patient had allergic reactions, it is advisable to give him diphenhydramine or another antihistamine drug for several days before the introduction of bilignost.
Contraindications for use are obstructive jaundice, acute liver and kidney diseases, decompensation of cardiac activity, pronounced forms of base disease.
Release form: in ampoules on 20 ml.
Storage: in a cool, dark place.
When storing bilignost solutions, crystals may precipitate or crystallize the contents of the ampoule. In these cases, the ampoule is heated in a water bath. If the crystals completely disappear and the solution becomes transparent, and when cooled to 36 - 38 ° C, the crystals do not drop out again, the solution is suitable for use.