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Description medications: Acignost

Pentagastrin (Pentagastrinum).

N-tert-butyloxycarbonyl-b-alanyl-L-tryptophyl-L-methionyl-L-asparaginyl-Lfenilalanilamid (pentapeptide).

Synonyms: Acignost, Gastrodiagnost, Pentagastrin, Peptavlon .

White or white with a slightly yellowish white amorphous powder odorless. Almost insoluble in water, very slightly soluble in alcohol.

It is a synthetic analogue of the digestive tract hormone - gastrin. It has the ability to greatly stimulate the secretion of stomach. Applied as a stimulant of gastric secretion for the diagnosis of diseases of the stomach (the definition of secretory capacity and function of the stomach acid-cm. And Histamine).

Used as a 0.025% solution. Enter under the skin at the rate of 6 micrograms (0.006 mg) per 1 kg of patient weight.

Secretion after administration is enhanced over 5 - 10 minutes, reaching a maximum after 15 - 30 minutes and lasts for 1 hour or more.

Investigation of the gastric juice is usually carried out every 15 minutes for 1 hour or more.

With the introduction of the drug may be excessive salivation, nausea, kratkovremennnoe a moderate decrease of blood pressure, discomfort in the abdomen.

Application pentagastrin contraindicated in circulatory failure II - III stage, cardiac arrhythmias, hypotension.

Product form: a solution in vials containing 0.5 mg (2 ml = 500 mg of drug).

Storage: List B. In the dark place at a temperature from +1 to +6 C