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Description of the medicine: Felbamate

FELBAMATE.

2-Phenyl-1,3-propanediol dicarbamate.

Synonyms: Felbatol, Felbatol.

The chemical structure has some similarities with the tranquilizer meprotan (see).

An anticonvulsant (antiepileptic) drug, differing in the mechanism of action in that it stimulates glycine (inhibitory) "binding sites" (receptors). It is at the same time an antagonist of aspartate (stimulating) receptors and blocks sodium channels of nerve cells.

Applied for different forms of epilepsy. Assign adults from 1.2 grams per day, gradually increase the daily dose to 3.6 g (not more); Children from 2 to 14 years - at a rate of 15 mg per 1 kg of body weight per day.

Product: tablets of 0.4 and 0.6 g; 60% slurry.

This foreign drug is not included in the State Register of Medicines of the Russian Federation, but it deserves attention from the point of view of the features of its neurochemical mechanism of action.