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Description of the medicine: Chophytol (Chophytol)

HOPHITOL (Chophytol)
Pharmacological action: A herbal preparation with choleretic, hepatoprotective and diuretic effects, reduces blood urea. Ascorbic acid, carotene, vitamins B1 and B2, inulin contained in artichoke (Cynara scolymus) contribute to the normalization of metabolism in the body. Chophytol increases the production of coenzymes by hepatocytes and affects the metabolism of lipids, cholesterol and ketone bodies. It has a detoxifying effect on the liver or kidney parenchyma during antibiotic therapy. Promotes the release of toxins from the body, including nitro compounds, alkaloids, salts of heavy metals.

Pharmacokinetics: The effect of the drug Hofitol is the combined effect of its components, so kinetic observations are not possible; collectively, components cannot be traced using markers or bioassays. For the same reason, it is impossible to detect the metabolites of the drug.

Indications:
- chronic jade;
- Severe renal impairment;
- oliguria in heart failure and cirrhosis;
- acetonemia;
- biliary dyskinesia according to the hypokinetic type;
- cholecystitis;
- chronic hepatitis;
- jaundice;
- chronic intoxication (including hepatotoxic substances, nitro compounds, alkaloids, salts of heavy metals);
- atherosclerosis;
- obesity.

Pregnancy and lactation: There are reports that the use of Hofitol in the complex treatment of preeclampsia improves the clinical course of the disease. It is believed that Hofitol can be recommended in a complex of preventive measures at a risk of developing gestosis in early pregnancy.
Data on the safety of the use of the drug Hofitol during lactation are not provided.

Contraindications: obstruction of the biliary tract.

Side effect: From the digestive system: diarrhea may develop with prolonged use of the drug in high doses.

Special instructions: With prolonged use of the drug in high doses, the risk of developing diarrhea increases.

Drug interaction: Drug interaction of the drug Hofitol is not described.

Overdose: Symptoms: may increase the manifestations of side effects.

Dosage and administration: Adults are prescribed 2-3 tablets. 3 times / day before meals. The course of treatment is 10-20 days, monthly.
If necessary, iv or intramuscular administration of the drug is prescribed: 1-2 injections or more per day, for 8-15 days.
The duration of use is set individually, depending on the indications.
Children, depending on age, are prescribed 1-2 tablets. 3 times / day before meals. If necessary, in / in or in / m administration appoint 1 / 4-1 / 2 of the dose used in adults.