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Description medications: Lornoxicam (Lornoxicam)

Lornoxicam (Lornoxicam).

6-Chloro-4-hydroxy-2-methyl-N-2-pyridyl-2H-thieno [2,3-e] -1,2-thiazine-3-carboxamide-1,1-dioxide.

Synonym: Ksefokam, Xefocam.

It belongs to the group of oxicams.

It has a pronounced anti-inflammatory and analgesic activity in particular (for action in post-operative pain and trauma are similar to morphine and is significantly superior to tramadol.).

When ingestion rapidly and completely absorbed, bioavailability reaches 100%, with max intramuscular and oral application of 15 min and 2 h, T1 / 2 - 4 hours; biotransformation in the liver, is derived mainly from the bile.

Assign arthritis (rheumatoid, psoriatic, gouty, infectious disease), ankylosing spondylitis, radicular syndrome, osteochondrosis, myalgia, postoperative and post-traumatic pain.

Administered orally or parenterally.

Inside designate before meals with plenty of water. Initial (1 Day) 0,016-0,032 g dose (16-32 mg), followed by 0.008 g (8 mg), 2 times a day.

For the relief of acute pain impose intramuscularly or intravenously at a dose of 0,008-0,016 g (8-16 mg).

It differs from "regular" NSAID less damaging effect on the gastrointestinal mucosa. However, when use of the drug can be observed: erosive and ulcerative lesions and bleeding in the gastrointestinal tract, dyspepsia, abnormalities in the kidneys and liver, drowsiness, depression or agitation, increased blood pressure, peripheral edema, sweating, leukopenia, thrombocytopenia, allergic skin reactions.

Contraindications: gastric ulcer and duodenal ulcer disease, inflammatory bowel disease, asthma, disorders of the liver and kidney failure, congestive heart failure, arterial hypertension, leukopenia, thrombocytopenia, pregnancy, breast-feeding, age and 18 years of age and older.

Other NSAIDs and indirect anticoagulants increase the risk of adverse effects of lornoxicam, which, in turn, enhances the hypoglycemic activity of sulfonylurea derivatives, weakens the diuretic effect and increases the nephrotoxicity of diuretics.

We recommend caution when engaging in potentially hazardous activities that require special attention and reaction speed.

Product: tablets of 0.004 and 0.008 g (4 and 8 mg) (N. 10, 20); lyophilized powder for injection solutions in vials of 0,008 grams (8 mg) (5 N. The).

Storage: List B.