Description medications: nabumetone (Nabumetone)
4- (6-Methoxy-2-naphthyl) -2-butanone.
Synonyms: Relafen, Rodanol S, Relafen, Rodanol S.
White or colorless crystalline powder. Insoluble in water, soluble in alcohol and other organic solvents.
The chemical structure and anti-inflammatory activity similar to naproxen. (cm.).
It has anti-inflammatory, analgesic and antipyretic effect.
When ingestion rapidly and completely absorbed, bioavailability of 80%, T1 / 2 - 24 hours; biotransformation in the liver, excreted by the kidneys.
Applied with rheumatoid arthritis and osteoarthritis.
Assign inside (regardless of meal times) 1g 1-2 times a day.
Possible side effects are basically the same as when using naproxen. Ulcerogenic effect is less pronounced.
Contraindicated in gastric ulcer and duodenal ulcer (in the acute period, and history), asthma, heart failure, peripheral edema, violations of the liver and kidneys, hemophilia.
It enhances the effects of anticoagulants, antiplatelet agents, and fibrinolytic agents, as well as the side effects of corticosteroids.
Product: pills to 0.5; 0.75 and 1 g (N. 20, 100).
Storage: List B.