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Description of the medicine: Nicotinum (Nicotinum)

NICOTINE (Nicotinum).

3- (1-Methyl-2-pyrrolidinyl) pyridine.

The alkaloid contained in the leaves of tobacco (Nicotiana tabacum). Has a stimulating effect on the central and peripheral n-cholinoreactive systems of the body. When smoking is absorbed and has a number of n-cholinostimulating effects, which contribute to addiction to tobacco smoking.

As a drug, nicotine has no application. However, in recent years, it has been established that when administered in small doses in the form of special dosage forms, it can facilitate the withdrawal from smoking. Previously, this property was found in other ganglionic stimulating alkaloids (lobeline, cytisine, anabasin).

The mechanism of action of all these alkaloids is due to their ability to bind to n-holinoretseptorami, preventing the binding of the latter with nicotine.

Currently, nicotine in the form of chewing gums (0.002 and 0.004 grams) and inhalation solution (0.01 g inhalers) under the name "Nicorette" and transdermal therapeutic systems "Nicotinella TTC" is used as a means to facilitate withdrawal from Smoking.

Apply 1 chewable tablet every 1-2 hours (up to 15 gum a day) for 3 months to 1 year; The plaster is applied to the skin, starting usually with a TTC of 10 (10 cm2). for a day. The course of treatment up to 3 months.