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Description of the medicine: Tiaprofenic acid (Tiaprofenic acid)

TIAPROPHENIC ACID (Tiaprofenic acid).

5-Benzoyl-A-methyl-2-thiophenoacetic acid.

Synonym: Surgam, Surgam.

It has anti-inflammatory, analgesic and antipyretic effects.

Suppresses the synthesis of prostaglandins.

Quickly absorbed in the digestive tract, Cmax is 1 hour, T1 / 2 - 2 hours; excreted by the kidneys in the form of metabolites.

They are used for rheumatoid arthritis, ankylosing spondylitis, osteoarthritis, extra-articular rheumatism (bursitis, etc.), lumbosacral radiculitis, and postoperative pain.

Assign inside, rectally and intramuscularly.

Inside (with food), adults take 0.3 g 2 times a day, children over 3 years old take 10 mg / kg per day (in 2-3 doses).

Rectally administered to adults 0.3 g, children 0.15 g 1-2 times a day.

Intramuscularly administered 0.2-0.4 g every 8 hours

Possible side effects: dyspepsia, ulcerogenic effect, impaired vision and hearing, insomnia, peripheral edema, etc.

The drug is contraindicated in patients with peptic ulcer of the stomach and duodenum, bronchial asthma, severe violations of the liver and kidneys, with inflammation of the bladder and prostate gland, pregnancy, breast-feeding.

Other NSAIDs increase the risk and severity of side effects of thiaprofenic acid.

Method of release: tablets of 0.1 g (N. 30) and 0.15 g (N. 6) for children and 0.3 g (N. 40); tablets and capsules retard 0.3 g; rectal suppositories of 0.15 g for children and 0.3 g (N. 6); powder for injection in vials of 0.2 g.

Storage: List B.