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Medication Description: Tiaprofenic acid

TIAPROFENOVA ACID (Tiaprofenic acid).

5-Benzoyl-A-methyl-2-thiophenoacetic acid.

Synonym: Surgam, Surgam.

It has anti-inflammatory, analgesic and antipyretic effects.

Suppresses prostaglandin synthesis.

Rapidly absorbed in the digestive tract, Сmax is 1 h, T1 / 2 - 2 h; excreted by the kidneys as metabolites.

Apply with rheumatoid arthritis, ankylosing spondylitis, osteoarthritis, extra-articular rheumatism (bursitis, etc.), lumbosacral radiculitis, with postoperative pain.

Assign inside, rectally and intramuscularly.

Inside (with meals) adults take 0.3 g 2 times a day, children over 3 years old take 10 mg / kg per day (in 2–3 doses).

Rectally prescribed adults for 0.3 g, children - 0.15 g 1-2 times a day.

Intramuscularly injected with 0.2-0.4 g every 8 hours.

Possible side effects: dyspepsia, ulcerogenic action, impaired vision and hearing, insomnia, peripheral edema, etc.

The drug is contraindicated in gastric ulcer and duodenal ulcer, bronchial asthma, marked disorders of the liver and kidneys, with inflammation of the bladder and prostate, pregnancy, breast-feeding.

Other NSAIDs increase the risk and severity of side effects of tiaprofenic acid.

Method of production: tablets of 0.1 g (N. 30) and 0.15 g (N. 6) for children and 0.3 g (N. 40); tablets and capsules retard 0.3 g; rectal suppositories of 0.15 g for children and 0.3 g (N. 6); powder for injection solutions in vials of 0.2 g

Storage: List B.