Description of the medicine: Etodolac (Etodolac)
1,8-Diethyl-1,3,4,9-tetrahydropyrano [3,4-b] indole-1-acetic acid.
Synonym: Elderin, Elderin.
White crystalline substance. Insoluble in water, soluble in organic solvents.
It has anti-inflammatory, analgesic and antipyretic effects.
It inhibits the formation of prostaglandins.
Quickly and completely absorbed, Cmax is 1-2 hours, T1 / 2 - 3.5-10 hours; undergoes biotransformation in the liver, excreted by the kidneys mainly in the form of metabolites.
The main indications: rheumatoid arthritis, rheumatism, ankylosing spondylitis, osteoarthritis, pain.
Assign inside (with food) 0.2-0.3 g 2 times a day (up to 2 g per day).
The main side effects: dyspepsia, ulcerogenic effect, bronchospasm, dysuria, inhibition of hematopoiesis, skin allergic reactions.
The drug is contraindicated in gastric ulcer and duodenal ulcer, pregnancy, breastfeeding.
Release form: tablets on 0,2-0,3 g (N. 20).
Storage: List B.