Description of the medicine: Mivacurium chloride

MIWAKURIUM CHLORIDE (Mivacurium chloride).

2,2'- [(1,8-dioxo-4-octene-1,8-diyl) bis (hydroxy-3,1-propanediyl)] bis [(1,2,3,4-tetrahydro-6.7 Dimethoxy-2-methyl-1 - [(3,4,5-trimethoxyphenyl) methyl]] - isoquinoline dichloride.

Synonym: Mivacron, Mivacron.

The chemical structure is similar to d-tubocurorine, also being a bis-quaternary derivative of tetrahydroisoquinoline.

A non-depolarizing muscle relaxant that differs from other non-depolarizing muscle relaxants with a short duration of action (in the body it is relatively quickly hydrolyzed by blood cholinesterase).

Like d-tubocurarine, myvacuria chloride causes the release of histamine from the tissues.

Enter the drug intravenously. The initial dose for intubation in adults and children from 7 months to 12 years is 0.1-0.2 mg / kg (bolus); In children aged 2-6 months - 0.1-0.15 mg / kg. For further miorelaxation, enter (adults and children) every 6-15 minutes to 0.1 mg / kg.

Infusion adults are injected at a rate of 8-10 μg / kg per minute, children - 11-14 μg / kg per minute.

Possible side effects: arterial hypotension, tachycardia, bronchospasm, skin allergic reactions.

Form release: 0.2% solution for injection in ampoules of 5; 10 and 25 ml.

Storage: List A.