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Description medications: terazosin (Terazosin)

Terazosin (Terazosin).

1- (4-Amino-6,7-dimethoxy-2-quinazolinyl) -4- (tetrahydro-2-furoyl) piperazine hydrochloride.

Synonyms: root, Setegis, Haytrin, Cornam, Hytrin, Setegis.

The white crystalline powder. It is soluble in water.

On chemical structure is very close to prazosin, differs only in the replacement of the furan ring in the tetrahydrofuran.

Long blocks postsynaptic A1-adrenoceptor vessels, prostate and bladder.

Quickly and completely absorbed in the digestive tract, bioavailability exceeds 90%, max of 1 hour, T1 / 2 - 12 hours, in connection with which the drug is prescribed 1 time per day; biotransformation in the liver, mainly in faeces.

Applied to treat hypertension and benign prostatic hyperplasia (see. Prazosin).

With arterial hypertension appoint from 0,001 g (1 mg) into the night (lying down), then gradually increase the dose to 0.005-0.01 g (5-10 mg) a day, watching the efficacy and tolerability.

In prostatic hypertrophy is also administered initially at a dose of 0.001 g (1 mg) overnight, then 0,002-0,01 g (2.10 mg) per day.

Possible side effects and precautions are the same as in the application of prazosin.

Product: pills to 0,001; 0.002; 0.005 and 0.01 g (1, 2, 5, and 10 mg) (N. 10, 20, 28).

Storage: List B.