Description of the medicine: Cetirizine (Cetirizine)
(±) - [2- [4- (p-Chloro-α-phenylbenzyl) -1-piperazonyl] ethoxy] acetic acid hydrochloride.
Synonyms: Zirtek, Cetrin, Cetrin, Zyrtec.
It is a metabolite of hydroxyzine (see).
Antagonist of H 1 -gistaminovyh receptors long-acting.
When ingestion is rapidly absorbed, C max is 1 h, T 1/2 - 7-10 h (with renal dysfunction - up to 20 h).
They are used for seasonal and chronic rhinitis, conjunctivitis, dermatosis, urticaria and Quincke's edema.
Assign inside adults and children over 6 years of 0.01 g once a day (in the evening) or 0,005 g 2 times a day (morning and evening); Children from 2 to 6 years - to 0,005 g (10 drops) once a day or 0,0025 g in the morning and in the evening.
Side effects occur rarely. Sometimes there is drowsiness, headache, dizziness, dry mouth, dyspepsia.
The drug is contraindicated in pregnancy and lactation.
Forms of release: tablets of 0.01 g (10 mg) (N. 7, 10, 20); 1% solution for oral administration in vials of 10 and 20 ml.