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Description of the medicine: Cetirizine (Cetirizine)

CETIRIZINE (Cetirizine).

(±) - [2- [4- (para-Chloro-α-phenylbenzyl) -1-piperazonyl] ethoxy] acetic acid hydrochloride.

Synonyms: Zyrtec, Cetrin, Cetrin, Zyrtec.

It is a metabolite of hydroxyzine (see).

Antagonist of H 1 -histamine receptors of long action.

When taken orally, it is rapidly absorbed, C max is 1 hour, T 1/2 - 7-10 hours (with impaired renal function - up to 20 hours).

They are used for seasonal and chronic rhinitis, conjunctivitis, dermatoses, urticaria and Quincke's edema.

Assign inside adults and children over 6 years of age, 0.01 g once a day (in the evening) or 0.005 g 2 times a day (morning and evening); children from 2 to 6 years old - 0.005 g (10 drops) once a day or 0.0025 g in the morning and evening.

Side effects are rare. Drowsiness, headache, dizziness, dry mouth, and dyspepsia are sometimes noted.

The drug is contraindicated in pregnancy and lactation.

Method of release: tablets of 0.01 g (10 mg) (N. 7, 10, 20); 1% oral solution in 10 and 20 ml vials.