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Description of the medicine: Lacidipine (Lacidipine)

LACIDIPINE.

4-tert-Butyl diethyl ester of 4- [ortho- [2-carboxyvinyl] phenyl] 1,4-dihydro-2,6-dimethyl-3,5-pyridinecarboxylic acid.

Synonym: Lacipil, Lacipil.

Refers to long-acting calcium channel blockers. Does not affect the automatism of the sinus node, myocardial contractility and the conduction system of the heart.

Quickly and completely absorbed in the digestive tract, although bioavailability does not exceed 10% (as a result of the "first pass" effect through the liver), C max is 30-150 min,
T S - 13-19 hours; Is excreted mainly with feces.

Applied with arterial hypertension.

Assign inside. The initial dose of 0.002 g (2 mg) 1 time per day (in the morning). After 3-4 weeks, the daily dose is increased if necessary to 0.004-0.006 g (4-6 mg).

Side effects and contraindications are the same as in nifedipine.

Form release: tablets of 0.002 and -, 004 g (N. 7, 14, 28, 56).