Medication Description: Simethicone
A mixture of poly (dimethylsiloxane) - dimethicone and silicone (silicon dioxide).
Synonyms: Gascon Drop, Disflatil, Sub Simplex, Simicol, Espumizan, Disflatyl, Espumisan, Gascon Drop, Sab simplex, Simicol.
Gray translucent viscous liquid. Insoluble in water and alcohol.
The drug belongs to the group of "defoamers", that is, substances that reduce the surface tension of gas bubbles. Used in the manufacture of drugs.
As a drug has been used to reduce the "foaming" of gastric juice and excessive gas formation in the intestine and facilitate the removal of gases from it. When ingestion is not absorbed, but passes into the intestine and reduces the surface tension of gases.
Applied with flatulence, reflux esophagitis, aerophagy, irritable bowel syndrome, as well as in preparing patients for diagnostic (radiological, ultrasound) studies of the stomach and intestines.
The drug is available in different forms and in various concentrations: Gascon Drop - in 1 ml of the emulsion 0.02 g (20 mg) of simethicone in vials of 300 ml; Displatil - in 1 ml of a solution (drop) of 0.04 g in 30 ml vials and chewable tablets of 0.01 g; Sab simplex - in 1 ml of suspension of 0.069 g in vials of 30 ml; Simicol - in 0.6 ml of a solution (drop) of 0.04 g in 30 ml vials; Espumizan - 0.04 g in 5 ml of the emulsion in vials of 100 ml and 0.04 g capsules
Displatil is prescribed for adults 25-50 drops or 0.04-0.08 g (1-2 tablets); children aged 6 to 15 years old - 15-20 drops or 0.04 g (1 tablet), younger children - 10-15 drops 2-3 times a day during or after meals.
Gascon Drop is taken by adults for 1 tablespoon 2 times a day.
Espumisan prescribed 1-2 teaspoons or 1-2 capsules 3-5 times a day.
In all cases, vials of emulsions (suspensions) must be shaken before use.
Simicol prescribed at 0.3-0.6 ml before each meal.
Potassium salt of simethicone is also produced, which is used in the form of tablets of 0.04 g and is used as an integral part of antacid agents (Asidopan, Gas X, Mylanta Gas Relief, Simeco, Di-Gel Liquid, Di-Gel Tablets, Maalox Plus, Riopan Plus and etc.).