Description of the medicine: Estriol (Estriol)
Estra-1,3,5 (10) -trien-3,16,17-triol, (16α, 17β).
Available in the form of disodium succinate.
Synonyms: Ovestin, Ortho-gynest, Ovestin, Ortho-gynest.
An estrogenic drug, similar in structure and action to estrone.
It is prescribed primarily for the restoration of vaginal epithelium, the pH of the environment and the vaginal microflora in case of disorders associated with estrogen deficiency, as well as with frequent urination, urinary incontinence, in the postmenopausal period.
Applied orally and intravaginally.
Inside, they are prescribed in the form of tablets at a dose of 0.002-0.008 g (2-8 mg) per day. Intravaginally administered in the form of a cream or suppository (0.5 mg) 1 time per day.
The duration of treatment should not exceed several weeks.
Possible side effects: pain in the mammary glands, swelling, nausea, spasms of the calf muscles, increased blood pressure, visual impairment, etc.
Contraindications: thrombosis, severe dysfunction of the liver, cholestatic jaundice, severe itching, uterine bleeding of unknown etiology, otosclerosis, estrogen-dependent tumors, pregnancy.
Method of release: tablets of 0.001 and 0.002 g (1 and 2 mg) (N. 30); 0.01% vaginal cream in tubes of 80 g and 0.1% - 15 g; vaginal suppositories of 0.5 mg (N. 3).
Storage: List B.