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Medication Description: Estriol (Estriol)

ESTRIOL (Estriol).

Estra-1,3,5 (10) -trien-3,16,17-triol, (16α, 17β).

Available in disodium succinate.

Synonyms: Ovestin, Ortho-Ginest, Ovestin, Ortho-gynest.

Estrogenic drug, similar in structure and action to estrone.

Assign mainly to restore the vaginal epithelium, pH and microflora of the vagina with disorders associated with estrogen deficiency, as well as with frequent urination, urinary incontinence, in the postmenopausal period.

Applied orally and intravaginally.

Inside prescribed in the form of tablets in a dose of 0.002-0.008 g (2-8 mg) per day. Intravaginally administered as a cream or suppository (0.5 mg) 1 time per day.

The duration of treatment should not exceed a few weeks.

Possible side effects: pain in the mammary glands, edema, nausea, gastrocnemius muscle cramps, increased blood pressure, visual impairment, etc.

Contraindications: thrombosis, marked disorders of the liver, cholestatic jaundice, severe itching, uterine bleeding of unknown etiology, otosclerosis, estrogen-dependent tumors, pregnancy.

Method of production: tablets of 0.001 and 0.002 g (1 and 2 mg) (N. 30); 0.01% vaginal cream in tubes of 80 g each and 0.1% - 15 g each; vaginal suppositories of 0.5 mg (N. 3).

Storage: List B.