Medication Description: Analginum (Analginum)
ANALGIN (Analginum). 1-Phenyl-2, 3-dimethyl-4-methylaminopyrazole-5-N-methanesulfonate sodium.
Synonyms , Diphon Sulpyrin, Toralgin, Totalgine, Vetalgin, etc.
White or white with a barely noticeable yellowish sheen crystalline powder. In the presence of moisture decomposes quickly. Easily soluble in water (1: 1, 5), it is difficult - in alcohol.
The aqueous solution (pH 6, 0-7, 5) is sterilized at + 100 ° C for 30 minutes.
Analgin has very pronounced analgesic, anti-inflammatory and antipyretic properties. As a well soluble and easily absorbed drug, it is particularly convenient for use in cases where it is necessary to quickly create a high concentration of the drug in the blood. Good solubility makes it possible to widely use analgin for parenteral administration.
Analgin is used for pains of various origins (headache, neuralgia, radiculitis, myositis), fever, flu, rheumatism, trochaic.
Assign analgin inside, intramuscularly or intravenously.
Inside taken after meals. Dose for adults - 0.25 - 0.5 g 2 - 3 times a day; with rheumatism - up to 1 g 3 times a day. Children inside 5 to 10 mg / kg 3 to 4 times a day.
Intramuscularly or intravenously (with severe pain) is administered to adults in 1 to 2 ml of 50% or 25% solution 2 to 3 times a day; no more than 2 g per day. Children are administered at the rate of 0.1-0.2 ml of a 50% solution or 0.2-0.4 ml of a 25% solution per 10 kg of body weight.
Subcutaneously do not apply, as irritation of tissues is possible.
Higher doses for adults inside: single 1 g daily 3 g; intramuscularly and into a vein: single 1 g daily 2 g.
When using analgin (especially for a long time), blood formation may be inhibited (granulocytopenia, agranulocytosis), therefore it is necessary to periodically conduct a blood test.
Cases of allergic reactions after taking analgin and anaphylactic shock after intravenous administration of the drug are described.
The drug is contraindicated in case of hypersensitivity (skin reactions, etc.), bronchiolospasm, hematopoietic disorders.
Method of issuance: powder, tablets of 0.5 g; 25% and 50% solutions in 1 and 2 ml ampoules.
For use in children's practice, tablets of 0.05 are also produced; 0.1 and 0.15 g
Storage: analgin and combined preparations containing it are stored according to B. List. In well-sealed jars of orange glass in a dark place.
R p.: Tab. Analgini 0.5 N.10
DS 1 tablet 2 - 3 times a day
R p. Sol. Analgini 50% 1 ml
Dtd N 6 in ampull.
S. 1 ml in the muscles
Tablets << Andipal >> (Tabulettae << Andipalum >>). They contain analgin 0.25 g, dibazol, papaverine hydrochloride and phenobarbital, 0.02 g each. Antispasmodic, vasodilator and analgesic. Apply mainly for vascular spasms, 1 to 2 tablets 2 to 3 times a day.
There are also ready-made tablets containing analgin and amidopirina 0.25 g, caffeine-sodium benzoate 0.1 g.
Anapyrin (Anapyrin) - tablets containing 0.25 g analgin and amidopirin, 0.1 g sodium caffeine-benzoate