Medication Description: Phosphocreatine (Fosfocreatine)
1- (2-Hydroxyethyl) phosphatilguanidine hydrogen phosphate.
Synonyms: Creatine phosphate, Creatine Phosphate, Neoton, Creatinfosfat, Neoton.
Phosphocreatine is a permanent component of the muscles (including myocardium). Plays an important role in ensuring the energy processes of the contractile activity of the musculature.
It improves myocardial metabolism, intracellular transport of energy, and suppresses the destruction of the sarcolemma of ischemic cardiomyocytes.
Phosphocreatine, obtained synthetically, is used as a "metabolic" agent in the complex therapy (and prevention) of various functional disorders of the myocardium, including those with chronic heart failure.
Injected intramuscularly at 0.5-1 g or intravenously at 1-2 g per day. In acute myocardial ischemia, it is administered intravenously: on day 1 - 2 g bolus, then 4 g per hour drip for 2 hours; in the 2-6th days - every day for 4-8 g.
The drug is usually well tolerated, but with rapid intravenous administration, a drop in blood pressure is possible.
Form release: lyophilized powder for injection solutions in vials of 0.5; one; 2 and 5 g complete with solvent (in ampoules).