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Description medications: Aztreonam (Aztreonam)

Aztreonam (Aztreonam).

(Z) -2 - [[[(2-Amino-4-thiazolyl) [[(2S, 3S) -2-methyl-4-oxo-1-sulfo-3-azetidinyl] carbamoyl] methylene] amino] oxy ] -2-methylpropanoic acid.

Synonyms: Azaktam, Azactam, Dynabiotic, Primbactam.

It has a bactericidal effect mainly on gram-negative aerobic bacteria. Relatively resistant to β-lactamases.

Apply with severe bacterial infections caused by Gram-negative organisms (urinary tract infections, lower respiratory tract infections, sepsis, abdominal and pelvic infections of the skin, soft tissues, bones and joints, otitis, etc.).

Enter intravenously or intramuscularly adults and 1 g every 8 hours or 2 g every 12 hours (for severe infections, including those caused by Pseudomonas aeruginosa, 2 g every 6-8 hours). The maximum daily dose of 8

Children are the rate of 30 mg / kg every 6-8 hours; in severe infections - 50 mg / kg (every 6-8 hours).

If the kidney function, reduce the dose.

For intramuscular injection is dissolved 1 g of the drug is not less than 3 ml of water for injection; intravenous - 6-10 ml.

You can not mix aztreonam with other antibiotics solution solutions.

Possible side effects include irritation of the tissues at the injection site, skin rash, nausea, diarrhea, thrombocytopenia, increased prothrombin time.

The drug is contraindicated in patients with renal and hepatic nedostatochnsoti, pregnancy, breastfeeding, newborn.

Product: powder for injection solutions in vials of 0.5 and 1 g (supplemented with L-arginine, 0.39 and 0.78 g, respectively).

Storage: List B.