Before taking the course, consult a doctor!
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Description of the medicine: Anastrozole (Anastrozole)
ANASTROZOL.
Α, α, αґ, αґ-Tetramethyl-5- (1H-1,2,4-triazol-1-ylmethyl) -meta-benzenediacetonitrile.
Synonym: Arimidex, Arimidex.
White crystalline powder. Poorly soluble in water, soluble in methanol, ethanol and acetone, easily soluble in acetonitrile.
It blocks the conversion of androgens to estradiol (in tumor cells of the breast) as a result of selective inhibition of the activity of aromatase.
When ingestion is well absorbed (up to 85%), C max is 2 h, T S is 50 h; Is biotransformation in the liver, excreted mainly by the kidneys.
Applied with estrogen-dependent breast tumors in women in the postmenopausal period.
Assign inside by 0,001 g (1 mg) 1 time per day.
Possible side effects: dyspepsia, anorexia, alopecia, arterial hypertension, thrombophlebitis, myalgia, arthralgia, anemia, leukopenia, drowsiness, allergic reactions.
Contraindications: estrogen-independent tumors, impaired liver and kidney function, pregnancy, breast-feeding.
Form release: tablets of 0.001 g (1 mg) (N. 14, 28).
Storage: List B.
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