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Description of the medicine: Valaciclovir (Valaciclovir)

Valaciclovir (Valaciclovir).

L-valine ester 9 - [(2-hydroxyethoxy) methyl] guanine.

Synonym: Valtrex, Valtrex.

White or colorless powder. Soluble in water.

Valine analog of acyclovir.

It is similar to acyclovir according to the antiviral mechanism.

Effective against herpes simplex viruses type 1 and type 2, herpes zoster and cytomegalovirus.

When taken orally, it is rapidly absorbed in the digestive tract, bioavailability is about 50%; C max - 1.5 hours, T Ѕ - 2.5-3.3 hours; in the intestine it undergoes hydrolysis with the formation of acyclovir and L-valine, excreted in the urine and feces for 4 days.

It is used for herpes zoster, skin and mucous membrane lesions caused by herpes simplex.

Assign inside adults: with herpes zoster - 1 g 3 times a day (for 7 days); with simple - 0.5 g 2 times a day (5-10 days); with genital - 0.5 g 2 times a day.

Possible side effects are the same as with acyclovir.

Release form: tablets on 0.25 g (N. 10, 60) and 0.5 g (N. 6.10).

Storage: List B.