Description of the medicine: Valaciclovir (Valaciclovir)
L-valine ester 9 - [(2-hydroxyethoxy) methyl] guanine.
Synonym: Valtrex, Valtrex.
White or colorless powder. Soluble in water.
Valine analog of acyclovir.
It is similar to acyclovir according to the antiviral mechanism.
Effective against herpes simplex viruses type 1 and type 2, herpes zoster and cytomegalovirus.
When taken orally, it is rapidly absorbed in the digestive tract, bioavailability is about 50%; C max - 1.5 hours, T Ѕ - 2.5-3.3 hours; in the intestine it undergoes hydrolysis with the formation of acyclovir and L-valine, excreted in the urine and feces for 4 days.
It is used for herpes zoster, skin and mucous membrane lesions caused by herpes simplex.
Assign inside adults: with herpes zoster - 1 g 3 times a day (for 7 days); with simple - 0.5 g 2 times a day (5-10 days); with genital - 0.5 g 2 times a day.
Possible side effects are the same as with acyclovir.
Release form: tablets on 0.25 g (N. 10, 60) and 0.5 g (N. 6.10).
Storage: List B.