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Description medications: Vinorelbine (Vinorelbine)
Vinorelbine (Vinorelbine).
3ґ, 4ґ-didehydro-4ґ-deoxy-8ґ-norvinkaleykoblastin.
Synonym: Navelbin, Navelbine.
White-yellow or light-brown amorphous powder. Soluble in water.
Semi-synthetic derivative of the alkaloid extracted from the periwinkle plant pink (Vinca rosea L.).
Available in the form of tartrate.
The structure and action close to vinblastine and vincristine.
Apply with lung cancer (except for small-cell), breast and ovarian cancer.
Enter intravenously (for 15-20 minutes). The usual dose (monotherapy) 25-30 mg / m 2, 1 time per week.
Ex tempore diluted in 125 ml of isotonic solution (0.9%) sodium chloride.
Possible side effects and contraindications are basically the same as that of vinblastine and vincristine.
Solution should guard against falling into the surrounding tissue (necrosis opportunity). Careful hematologic monitoring.
Product: 1% solution in bottles of 1 and 5 ml.
Storage: List B.
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