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Description of the medicine: Gemcitabine (Gemcitabine)
GEMCITABIN (Gemcitabine).
2ґ-2ґ-Difluorocytidine.
Synonym: Gemzar, Gemzar (hydrochloride).
A white or off-white substance. Soluble in water, sparingly soluble in methanol.
Anti-metabolite of deoxycytidine (inhibits ribonucleotide reductase).
The structure is close to cytarabine (fluorinated analog).
Applied with cancer of the pancreas, lungs, ovaries, breast, prostate.
Enter strictly intravenously at 1-1.25 g / m 2 at 1, 8, 15 days previously untreated patients and at 0.8 g / m 2 patients who have already undergone chemotherapy.
The drug can cause myelosuppression, nausea, vomiting, paresthesia, proteinuria, arrhythmias, alopecia, edema and other side effects.
Contraindicated in myelosuppression, violations of liver and kidney function, pregnancy, breast-feeding, in childhood.
Form release: lyophilized powder for injection solutions in vials of 0.2 and 1 g.
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