Medication Description: Sodium Salicylate (Natrii salicylas)
SODIUM SALICYLATE (Natrii salicylas).
Sodium salt of ortho-oxybenzoic acid.
Synonyms: Natrium salicylicum, Enterosal, Enterosalyl, Glutosalyl, Nadisal, Saliglutin, Salicine, Salitin, Sodium salicylate, etc.
White crystalline powder or small scales, odorless, sweet-salty taste. Very easily soluble in water (1: 1), soluble in alcohol (1: 6). Solutions (pH 6, 0-7, 0) are sterilized at + 100 ° C for 30 minutes.
It has analgesic, antipyretic and anti-inflammatory effect.
As an analgesic and antipyretic, sodium salicylate is prescribed for adults inside (after meals) at a dose of 0.5 - 1 g per dose; children under the age of 1 year old - 0.1 to 0.15 g each, up to 2 years old - 0.2 g, 3–4 years old - 0.25 g, 5–6 years old - 0.3 g, 7–9 years old - 0.4 g, 10-14 years old - 0.5 g 2 - 3 times a day.
In acute rheumatism, rheumatic endocarditis and myocarditis, the drug is used in the first days in large doses: adults are prescribed 6 to 10 g per day, then, with improvement, 4 g per day.
More often for oral administration appoint acetylsalicylic acid. Sometimes (especially with rheumatic endocarditis) sodium salicylate is administered intravenously in a dose of 5 to 10 ml of a 10% solution 1 to 2 times a day. Sometimes 3 - 5 - 10 ml of a 40% solution of hexamethylenetetramine is simultaneously administered. Intravenous should be administered slowly. In children with acute attacks of rheumatism, 0.5 g is prescribed for each year of life per day, but not more than the total daily dose of 6 g. Treatment with rheumatism salicylates is carried out for a long time course dose for adults reaches 300 - 350 g.
When sodium salicylate is used, the same side effects may occur as with acetylsalicylic acid.
Precautions and contraindications, see. Acetylsalicylic acid.
Method of issuance: powder; tablets of 0.25 and 0.5 g; 10% solution in ampoules of 5 and 10 ml.
Storage: in a well-closed container, protected from light, in a dry place; tablets - protected from light.
Rp .: Tab. Natrii salicylatis 0,25 (0,5)
DS 1 tablet 3-4 times a day after meals
Rp .: Sol Natrii salicylatis 5% 200 ml
DS 1 tablespoon in 2 - 3 hours
Rp .: Natrii salicylatis 0.3
DtdN 10 in tab.
S. 1 tablet 3-4 times a day after meals
Rp .: Sol. Natrii salicylatis 10% 5 ml
DtdN 6 in ampull.