Description of the medicine: Sodium salicylate (Natrii salicylas)
SODIUM SALICYLATE (Natrii salicylas).
Sodium salt of ortho-oxybenzoic acid.
Synonyms: Natrium salicylicum, Enterosal, Enterosalyl, Glutosalyl, Nadisal, Saliglutin, Salicine, Salitin, Sodium salicylate, etc.
White crystalline powder or small flavourless flakes, sweet-salty taste. Very soluble in water (1: 1), soluble in alcohol (1: 6). Solutions (pH 6, 0 - 7, 0) are sterilized at + 100 ° C for 30 minutes.
It has analgesic, antipyretic and anti-inflammatory effects.
As an analgesic and antipyretic, sodium salicylate is prescribed to adults inside (after eating) at 0.5 - 1 g per reception; children under the age of 1 year - 0.1 - 0.15 g, up to 2 years - 0.2 g, 3 - 4 years - 0.25 g, 5 - 6 years - 0.3 g, 7 - 9 years - 0.4 g, 10-14 years - 0.5 g 2 - 3 times a day.
In acute rheumatism, rheumatic endocarditis and myocarditis, the drug is used in the first days in large doses: adults are prescribed 6-10 g per day, then, when the condition improves, 4 g per day.
More often, acetylsalicylic acid is prescribed for oral administration. Sometimes (especially with rheumatic endocarditis) sodium salicylate is administered intravenously in 5-10 ml of a 10% solution 1 to 2 times a day. Sometimes 3 - 5 - 10 ml of a 40% solution of hexamethylenetetramine are simultaneously administered. Intravenously should be administered slowly. Children with acute attacks of rheumatism are prescribed 0.5 g for each year of life per day, but not more than the total daily dose of 6 g. Treatment with rheumatism salicylates is carried out for a long time. The adult dose reaches 300 - 350 g.
When using sodium salicylate, the same side effects can be observed as with the use of acetylsalicylic acid.
Precautions and contraindications see Acetylsalicylic acid.
Method of release: powder; tablets of 0.25 and 0.5 g; 10% solution in ampoules of 5 and 10 ml.
Storage: in a well-sealed container, which protects from the action of light, in a dry place; tablets - in a dark place.
Rp .: Tab. Natrii salicylatis 0.25 (0.5)
DS 1 tablet 3 to 4 times daily after meals
Rp .: Sol Natrii salicylatis 5% 200 ml
DS 1 tablespoon after 2 - 3 hours
Rp .: Natrii salicylatis 0.3
DtdN 10 in tab.
S. 1 tablet 3 to 4 times a day after meals
Rp .: Sol. Natrii salicylatis 10% 5 ml
DtdN 6 in ampull.