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Description of the medicine: Capreomycin (Capreomycin)
CAPROMOMYCIN (Capreomycin).
Synonym: Capastat, Capastat.
A polypeptide complex isolated from Streptomyces capreolus (a mixture of capreomycin IB and small amounts of capreomycin IIA and IIB). Let's dig in the water.
Has selective activity against mycobacteria tuberculosis.
When ingested poorly absorbed in the digestive tract; When administered intramuscularly, C max is 1-2 hours, T S is 3-6 hours; Not subject to biotransformation, excreted by the kidneys.
Refers to standby anti-tuberculosis drugs.
Assign (in combination with other anti-TB drugs) intramuscularly (deep) or intravenously at 15-16 mg / kg (in 2 ml of 0.9% sodium chloride solution) daily (up to 1 g) for 2-3 months.
There is cross-resistance to kanamycin, amikacin, but not to streptomycin.
Has oto-, nephro- and hepatotoxic effects; Dyspepsia, neuromuscular conduction disorder, leukopenia or leukocytosis, hypokalemia, hypocalcemia, hypomagnesemia, allergic reactions are also possible; At the injection site - infiltrates, sterile abscesses, soreness.
Under the experimental conditions, it exhibits a teratogenic effect.
The drug is contraindicated in pregnancy, breast-feeding, in childhood.
Form release: lyophilized powder for injection solutions in vials of 1 g.
Storage: List B.
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