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Medication description: Midecamycin (Midecamycin)

MIDEKAMYCIN (Midecamycin).

Synonym: Macropen, Macropen.

Antibiotic group macrolides.

Has a wide range of action. It is active against gram-positive (staphylococcus, streptococcus, causative agent of diphtheria, listeria, etc.) and gram-negative bacteria (helicobacter, campylobacter, hemophilic rod, etc.) of bacteria, anaerobes (bacteroides, clostridia) and intracellular pathogens (mycoplasmas, chlamydia, legionella and Other).

After oral intake quickly and completely absorbed, C max is 1-2 hours; Accumulates in the lungs, parotid and submaxillary glands, skin; Undergoes biotransformation in the liver, is excreted primarily with bile.

Applied with infections of the respiratory system and the genitourinary system caused by intracellular microorganisms; Infections of the respiratory system, skin and subcutaneous tissue caused by penicillin-sensitive bacteria; With enteritis caused by Campylobacter, as well as for the treatment and prevention of pertussis and diphtheria.

Assign adults to adults for 0.4 g 3 times a day, children - 20-50 mg / kg (2-3 reception). The course of treatment is 7-10 days (for chlamydial infections - 14 days).

Possible side effects: dyspepsia, eosinophilia, skin allergic reactions.

The drug is contraindicated in severe hepatic insufficiency.

Forms of release: tablets of 0.4 g (N. 8); Powder for a 3.5% suspension for oral administration.

Storage: List B.