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Description of the medicine: Nelfinavir (Nelfinavir)

NELFINAVIR (Nelfinavir).

(3S, 4aS, 8aS) -N-tert-Butyl-2 - [(2R, 3R) -3- (3,2-cresotamido) -2-hydroxy-4- (phenylthio) butyl] decahydro-3-isoquinoline- carboxamide methanesulfonate.

Synonym: Virasept, Virasept.

Active against HIV-1 and HIV-2 proteases.

Quickly and almost completely (up to 80% of the dose) is absorbed into the digestive tract, C max is 2-4 hours, T Ѕ - 2.5-5 hours; undergoes biotransformation in the liver, excreted mainly with feces.

Used in the treatment of HIV infection.

Assign inside adults and children over 13 years of age at 0.75 g, children under 13 years of age at the rate of 20-30 mg / kg 3 times a day.

Possible side effects: dyspeptic symptoms, impaired liver function, neutropenia.

Contraindicated in pregnancy and lactation.

Method of release: tablets of 0.25 g (N. 180, 270), powder in bottles of 144 g (0.05 g of the drug in 1 g) complete with a measuring spoon.

Storage: List B.