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Description medications: Roferon A (Roferon A)

Roferon A (Roferon A).

Recombinant α-2a, interferon synthesized in the culture of Escherichia coli.

According to the action and indications for use close to the IFN.

Assign intramuscularly and subcutaneously.

When hairy leukemia are administered 3 million IU daily for 16-24 weeks; maintenance dose for 3 000 000 IU three times a week.

For T-cell lymphoma, in the first 3 days appoint 3 000 000 IU, 4-6 th days - at 9,000,000 IU in 7-84 minutes - at 18 000 000 IU; maintenance dose of up to 18 million IU three times per week.

In Kaposi's sarcoma in HIV infection are administered 3 million IU in the first 3 days, 4-
6th days - at 9,000,000 IU in 7-9 minutes - at 18 000 000 IU; with good tolerability in the future (84-day) dose increased to 36 million IU; maintenance dose - not more than 36 million IU three times per week.

In cancer of the kidneys is used by 18 million - 36 million IU per day for 84 days.

Melanoma appoint 18 million IU three times per week for 8-12 months.

In chronic myelogenous leukemia administered on the first three days at 3,000,000 IU 4-6 on days - at 6,000,000 IU and days 7-84 minutes - at 9,000,000 IU per day.

In chronic active hepatitis B is used for 4.5 million IU three times per week for 6 months.

In chronic hepatitis C designate 6 000 000 IU three times a week for 3 months and then at 3 000 000 IU for a further 3-9 months.

When administered by meolomnoy disease 3 000 000 IU three times a week, weekly increasing to the maximum tolerated dose (9 000 000 - 18 000 000 IU).

Possible side effects: "flu-like" syndrome, blurred vision, swelling, dizziness.

Contraindications: severe cardiovascular disease in history, severe violations of the hematopoietic system, liver and kidneys, central nervous system diseases.

Product: dried powder for injection solutions in vials of 3 000 000, 4 500 000 6 000 000 9 000 000 18 000 000 IU in unit-dose syringes 3 000 000 4 500 000 6 000 000 9 000 000 IU.

Storage: List B.