Description of the medicine: Spiramycin (Spiramycin)
Synonym: Rovamycin, Rovamycin.
Natural antibiotic of the macrolide group.
It has a bacteriostatic effect against streptococci, pneumococci, staphylococci, meningococci, gonococci, legionella, listeria, clostridia, mycoplasmas, toxoplasmas, chlamydia, leptospira, campylobacteria and other microorganisms. Enterobacter and pseudomonas are resistant to it.
Quickly absorbed by ingestion (after 30 minutes), C max is 1.5-3 hours, T Ѕ - 8 hours, penetrates well into organs and fluids, is metabolized in the liver (very slowly), excreted mainly with bile.
It is prescribed for infections of the respiratory tract, urinary tract, ENT organs, pelvic organs, bones, joints, skin and soft tissues, toxoplasmosis, chlamydia, syphilis, gonorrhea, for the prevention of acute articular rheumatism and meningitis, with bacteriocarrier of pertussis and diphtheria.
Applied orally and intravenously.
Inside (before meals), adults are prescribed for 6,000,000 - 9,000,000 IU (2-3 g) per day (in 2 divided doses), for children weighing up to 10 kg - 750,000 - 1,500,000 IU, 10-20 kg - 1,500,000 - 3,000,000 IU and more than 20 kg - at the rate of 1,500,000 IU per 10 kg of body weight per day (in 2-3 doses). The course of treatment is 7-14 days.
4,500,000 to 9,000,000 IU (1.5-3 g) are administered intravenously (only for adults) per day (in 3 divided doses).
Possible side effects: nausea, vomiting, diarrhea, allergic reactions (skin rash).
Contraindication: severe impaired liver function. It is not recommended to prescribe the drug during lactation.
Method of release: tablets of 1,500,000 IU (N. 16) and 3,000,000 IU (N. 10); granules for suspension for oral administration for children of 375,000, 750,000 and 1,500,000 IU; powder for injection in bottles of 1,500,000 IU.
Storage: List B.