Medication Description: Spiramycin (Spiramycin)
Synonym: Rovamycin, Rovamycin.
Natural antibiotic macrolide group.
It has a bacteriostatic effect on streptococci, pneumococci, staphylococci, meningococci, gonococci, legionella, listeria, clostridia, mycoplasma, toxoplasma, chlamydia, leptospir, campylobacter and other microorganisms. Enterobacter and pseudomonas are resistant to it.
It is rapidly absorbed by ingestion (after 30 minutes), C max is 1.5-3 hours, T Ѕ - 8 hours, penetrates well into organs and fluids, is metabolized in the liver (very slowly), excreted mainly with bile.
It is prescribed for infections of the respiratory tract, urinary tract, upper respiratory tract, pelvic organs, bones, joints, skin and soft tissues, toxoplasmosis, chlamydia, syphilis, gonorrhea, for the prevention of acute articular rheumatism and meningitis, for whooping cough and diphtheria.
Apply inside and intravenously.
Inside (before meals) is prescribed for adults at 6,000,000 - 9,000,000 IU (2-3 g) per day (in 2 doses), for children weighing up to 10 kg - 750,000 - 1,500,000 IU, 10-20 kg - 1 500 000 - 3 000 000 IU and more than 20 kg - at the rate of 1 500 000 IU per 10 kg of body weight per day (in 2-3 doses). The course of treatment is 7-14 days.
Intravenous (adults only) is administered at 4 500 000 - 9 000 000 IU (1.5-3 g) per day (in 3 doses).
Possible side effects: nausea, vomiting, diarrhea, allergic reactions (skin rash).
Contraindications: severe violations of the liver. It is not recommended to prescribe the drug during lactation.
Method of production: tablets of 1 500 000 IU (N. 16) and 3 000 000 IU (N. 10); granules for oral suspension for children of 375 000, 750 000 and 1 500 000 IU; powder for injection solutions in bottles of 1 500 000 IU.
Storage: List B.