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Description medicines: Finasteride (Finasteride)

Finasteride (Finasteride).

N-tert-Butyl-3-oxo-4-aza-5α-androst-1-ene-17β-carboxamide.

Synonyms: Proscar, Finasta, Finast, Proscar.

The white crystalline powder. Insoluble in water.

Synthetic azasteroid compounds having the specific ability to inhibit 5-α-reductase and the conversion of testosterone to dihydrotestosterone (decrease in blood is observed in the last 24 hours after drug administration).

When ingestion rapidly and completely absorbed in the digestive tract, bioavailability of 80%, C max - 1-2 h, T ½ - 6-8 hours; excreted in the urine and faeces.

Apply with prostate cancer.

Finasteride can inhibit the growth of prostate, improve urinary flow in its hypertrophy, alleviate symptoms associated with BPH. With prolonged use of marked decrease in prostate size.

Assign inside (before or during a meal) to 0,005 g (5 mg), 1 times a day for several months.

The clinical effect develops rapidly in some cases, in others - a few months.

Usually the drug is well tolerated. Perhaps decreased libido, increased nipple and pain.

Contraindications: obstructive uropathy, prostate cancer, pregnancy, child.

Avoid getting the drug (including the work of its manufacture) in the body of pregnant women (the risk of teratogenic effects - violation of the genital organs of male fetuses).

Product: pills to 0,005 grams (5 mg) (N. The 10, 28, 30).

Storage: List B.