Medication Description: Trimetazidine (Trimetazidine)
1- (2,3,4-Trimethoxybenzyl) piperazine.
Available as dihydrochloride.
Synonyms: Preductal, Cartoma, Hiwell, Lubomail, Preductal, Trimeperad, Trisedine, Vastarel, etc.
Quickly and completely absorbed in the digestive tract, T 1/2 is about 6 hours; Biotransformation in the liver, excreted by the kidneys.
Used for the prevention of strokes in coronary artery disease, as well as dizziness caused by impaired cerebral circulation, Meniere's disease, tinnitus.
Data on the effectiveness of the drug in acute myocardial infarction are contradictory.
It is believed that the beneficial effect of trimetazidine in myocardial ischemia is mainly due to its antioxidant and antihypoxic properties and the cytoprotective effect on cardiomyocyte functions.
Is taken orally (with meals) to 0.02 g (20 mg) 3 times a day.
Contraindicated in pregnancy and lactation.
Product form: tablets of 0.02 g (N. 30.60) and retard tablets of 0.035 g.