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Description of the medicine: Vitamin D3 (cholecalciferol) - aqueous solution ()

VITAMIN D 3 (cholecalciferol) is an aqueous solution.

Synonym: Colecalciferol, Colecalciferol

Vitamins of group D ergocalciferol and cholecalciferol are fat soluble substances and are used in the form of oily solutions; They are also included in the dragee tablets. Recently, a water-soluble dosage form of cholecalciferol (vitamin D 3 ), convenient for oral administration and highly effective in the prevention and treatment of rickets and other pathological conditions associated with deficiency in the body of vitamin D.

When ingested, the drug is rapidly absorbed (5 times faster than oily solutions), creates a high concentration of vitamin D in the body and has a long-lasting effect.

The therapeutic effect of the drug, as well as the action of endogenous vitamins D (ergocalciferol and cholecalciferol), is due to the regulation of calcium and phosphate metabolism. Vitamin D 3 promotes the absorption of calcium and phosphate from the intestine, regulates their participation in the calcification of bone tissue, slows the excretion of calcium and phosphorus ions from the body. Regulating influence on the metabolism of calcium and phosphorus ions explains other features of the drug: regulation of the processes of nervous excitation, muscle tone, blood coagulation, etc. (see Calcium preparations and agents for the treatment of osteoporosis).

Apply vitamin D 3 (cholecalciferol) - an aqueous solution with the following indications: prevention and treatment of rickets; Hypocalcemia tetany; Hypoparathyroidism; Osteomalacia and osteoporosis, including the prevention and treatment of osteoporosis, associated with hormonal disorders in women in menopause.

Assign inside as a drop.

For postnatal specific prevention of rickets in term infants, the minimum dose is 400-500 IU (1 drop) per day. This dose is used from 3-4 weeks of age in the autumn-winter and spring periods during the first two years of life, taking into account the conditions of the child's existence and the risk factors for the development of the disease. Children at risk for rickets are given 1000 ME (2 drops) every day at the same time. When I degree is premature, 400-1000 IU (1-2 drops) are administered daily, starting from the 10th to 14th day of life during the first two years (excluding summer months), with II-III prematurity 1,000-2000 ME ( 2-4 drops) daily in the first year of life and 500-1000 IU (1-2 drops) in the second year of life (excluding the summer months).

For the treatment of rickets, 2000-5000 IU (4-10 drops) are usually administered daily for 30-45 days, after which they pass to a maintenance dose (500 ME) once a day for two years and in the winter period in the third year of life A dose of 5000 IU is used only with pronounced bone changes). After 3 months after the end of the first course, children at risk are re-conducted an anti-relapse course (2000-5000 ME) for 3 to 4 weeks (except for the summer months).

With proper dosing, the drug is well tolerated.