Description medications: Dimexidum (Dimexidum)
Synonyms: DMSO, Brosorb, Damul, Deltan, Demasorb , Demavet, Dermasorb, Dimethylsulfoxid, DMSO, Dolicur, Dolocur, Dromisol, Durasorb, Hyadur, Mastan, Somipront, Syntexan and others.
Colorless transparent liquid or colorless crystals (melting temperature + 18, 5 C), with a specific smell. Hygroscopic. Miscible in all proportions with water and alcohol.
The external agent for topical application in inflammatory and other diseases (mainly in diseases of the musculoskeletal system).
The preparation has the ability to penetrate biological membranes, including skin through barriers. The basis for the use in inflammatory diseases of the musculoskeletal system is its analgesic and anti-inflammatory effect. The drug has a mild antiseptic and anti-fibrinolytic effect. It also enhances the skin penetration of some drugs.
Applied dimexide in undiluted form or in the form of solutions (10 - 30 - 50 - 70%) in double distilled water to reduce inflammation and pain phenomena in complex therapy of rheumatoid arthritis, ankylosing spondylitis deformans osteoarthritis, arthropathies, and bruises , sprains, traumatic infiltrates and others. also used in the treatment of erythema nodosum. In combination with the heparin used for thrombophlebitis, in combination with antimicrobials (liniment sintomitsina etc.) - In treatment of systemic sclerosis, furunculosis, erysipelas and acne, etc..
There is evidence of therapeutic efficacy Dimexidum with rheumatoid arthritis and deforming osteoarthritis, especially when combined with non-steroidal anti-inflammatory drugs.
Apply dimexide in the form of applications. The appropriate concentration of the solution - (usually 50% solution, and the skin of the face and other sensitive areas of the skin - 10 - 30% solution) moistened wipes, which are applied to the affected area for 20 - 30 minutes, 1 time per day; cloth covered with plastic wrap, and on top - cotton or linen cloth. The course of treatment - 10 - 15 daily treatments.
Usually the drug is well tolerated, but some patients may cause itchy dermatitis; some patients do not take the smell of the drug (nausea, retching), and in rare cases can bronhiolospazm.
The drug is contraindicated in violation of antitoxic function of the liver and renal excretory function, angina, atherosclerosis, pregnancy, glaucoma, cataract. Due to the fact that dimexide can enhance not only the activity but also the toxicity of certain drugs, caution should be exercised when administered concomitantly with other drugs.
Given the possibility of individual intolerance of the drug, the dosage recommended test for tolerance to it.