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Description medications: spazmolitin (Spasmolytinum)

Spazmolitin (Spasmolytinum). ~ -Dietilaminoetilovogo Ester 1, 1-diphenyl hydrochloride acid.

Synonyms: Difatsil, Adiphenin, Trasentin, Vagospasmyl, Veganthin .

The white crystalline powder salty-bitter taste. Easily soluble in water. The dry rack, aqueous solutions gradually hydrolyze,

It has peripheral m-holinoliticheskoy activity; moreover, it has a blocking effect on the n-holinoreaktivnye. It has antispasmodic activity: relaxing the smooth muscles of internal organs and blood vessels; It is also a local anesthetic.

Apply at pilorospazme, spasmodic colic, gallstones, renal colic, gastric ulcer and duodenal ulcers, angina, endarteritis, and neuralgia, neuritis, radiculitis. There is evidence of efficacy in itching dermatoses, as well as migraine.

Assign spazmolitin orally after meals for 0.05 - 0.1 g of 2 - 3 - 4 times daily. The course of treatment 3 - 4 weeks.

When using spazmolitin (as well as other anticholinergics) should be selected dose individually. In case of overdose may appear dizziness, headache, feeling of intoxication (due to central action), dry mouth (due to peripheral anticholinergic effect), disturbance of accommodation.

Providing an irritating effect on the gastric mucosa, spazmolitin can cause dyspepsia.

The feeling of intoxication and dizziness can prevent or reduce caffeine assignment (0.1 - 0.2 g caffeine-sodium benzoate into or 1 ml of a 20% solution under the skin).

Spazmolitin and close to it drugs (Arpenans et al.) Should not be taken before and during transport drivers and others whose profession requires quick mental and physical reactions.

Contraindicated in glaucoma.

Product: powder.

Storage: List B. In dry, dark place.

Abroad, called "Neuro-Trasentin" produced tablets containing 0.03 g trazentina (spazmolitin) and 0.04 grams of phenobarbital. Applied as a sedative and holinoliticheskoe means (with nervousness, increased excitability, functional disorders of the gastrointestinal tract).