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Description of the medicine: Quateronum
Quateronum. , -Dimethyl-α-diethylaminopropyl ester of p-butoxybenzoic acid, iodoethylate.
White powder with a slightly yellowish tinge, bitter taste. Soluble in water with gentle heating.
Refers to mono-quaternary ammonium compounds, which exert a ganglion-blocking effect.
The drug blocks the excitation in the parasympathetic and, to a lesser extent, sympathetic ganglia.
It also has some coronary expansive action.
Applied mainly with peptic ulcer of the stomach and duodenum, sometimes - with stenocardia and hypertension.
Assign inside in the form of tablets or an aqueous 0.6% solution.
With gastric ulcer, take 0.02-0.03 g (1 - 1, 5 tablets or 5 ml of 0.6% solution) 3 to 4 times a day. The course of treatment 3 - 4 weeks or more.
For angina pectoris, to prevent seizures, appoint, starting with 0.01 g (10 mg) per reception, after 2 - 3 days a single dose is increased to 0.02 g. Accepted 3 times, and with frequent attacks 4 times a day. The course of treatment 3 - 4 weeks. Treatment can be repeated after a 10 - 12-day break.
In hypertensive illness, 0.02-0.03 g is prescribed 3 to 5 times a day; Course of treatment on average 3 weeks.
Higher doses for adults inside: single 0.05 g, daily 0.2 g.
When taking a quater, there may be side effects: dizziness, a tendency to constipation, mild tachycardia. In patients with peptic ulcer, sometimes in the first days, pain in the epigastric region and dyspeptic phenomena are noted. Patients with angina pectoris sometimes have unpleasant sensations in the region of the heart, frequent attacks; In these cases the drug is canceled for 2 to 6 days, then it is prescribed in smaller doses; If the side effects do not stop, the drug is canceled. Caution should be observed when assigning a quaterone to patients with arterial hypotension.
Form release: powder and tablets of 0.02 g.
Storage: List B. In a well-ukuporennoy packaging, protecting from the effects of light.
RR .: Tab. Quateroni 0.02 N. 50
DS 1 tablet 3 times a day
RR: Sol. Quateroni 0,6% 100 ml
DS
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