Description of the medicine: Benzobamil (Benzobamilum)
BENZOBAMIL (Benzobamilum). 1-Benzoyl-5-ethyl-5-isoamylbarbituric acid.
Synonyms: Benzamyl, Benzoylbarbamyl.
White crystalline powder. Practically insoluble in water, easily soluble in alcohol.
Chemically different from benzonal in that the phenyl radical at position 5 is replaced by an isoamyl radical.
It has an anticonvulsant, sedative effect. In large doses, it can cause sleeping pills. Somewhat less toxic than benzonal.
Applied with epilepsy with localization of the focus of excitation mainly in subcortical formations. With cortical forms, it is less active. It is ineffective in non-convulsive forms. With subcortical localization of the epilepsy focus, the drug gives a good therapeutic effect; It has not only an anticonvulsant effect, but improves the overall mental state (reduces or relieves headaches, lethargy, mood swings, etc.).
Take orally after a meal. The dose for adults is 0.05 - 0.2 g (up to 0.3 g) 2 - 3 times a day, for children, depending on age, from 0.05 to 0.1 g 3 times a day.
The equivalent ratio of benzobamyl and phenobarbital is 2-2, 5: 1.
Like phenobarbital and benzonal, benzobamil increases the activity of the monooxidase enzyme system of the liver.
Contraindications and precautions are the same as for benzonal.
Release form: tablets of 0.1 g in a package of 100 pieces.
Storage: List B.