Description of the medicine: Atracurium (Atracurium)
ATRAKURIUM (Atracurium) *.
A synthetic bis-quaternary ammonium compound having a partial structural similarity with tubocurarine and dithilin molecules.
Synonyms: Tracrium, Tracrium.
It is a non-depolarizing muscle relaxant. The nature of the action is similar to other drugs in this group. It has a quick, easily reversible muscle-relaxing effect. It has a low ability to cumulate.
After intravenous administration at a dose of 0.5 - 0.6 mg / kg for 90 s, the opportunity for intubation is created. At a dose of 0.3 - 0.6 mg / kg causes muscle relaxation lasting 15 - 35 minutes. Additional doses from 0.1 to 0.2 mg / kg prolong relaxation for 15 to 35 minutes. The drug can also be administered as an infusion at a rate of 0.005-0.01 mg / kg per minute.
The drug is removed by the administration of prozerin (with atropine) or other anticholinesterase drugs.
Usually, the drug is well tolerated, no changes in the cardiovascular system are observed. Due to the possibility of histamine release, slight skin hyperemia, in rare cases, bronchospasm, anaphylactic reactions can be observed.
Contraindications and general precautions are the same as for other non-depolarizing muscle relaxants.
Release form: 1% solution (transparent pale yellow liquid) in ampoules of 5 and 2.5 ml (50 and 25 mg).