Description medications: fenoterol (Fenoterolum)
Fenoterol (Fenoterolum) *. 1- (3, 5-dihydroxyphenyl) -2- (p-hydroxy-a-methyl-phenethylamino) ethanol.
Available in the form of hydrobromide.
Synonyms: Berotek, Partusisten, Airum, Berotec, Dosberotec, Partusisten , Segamol and others.
The structure and action close to ortsiprenalin, but is more selective adrenoceptor blocker b 2, and has therefore more selective, strong, relatively prolonged action when bronchospastic states with fewer adverse events (tachycardia and other disorders of the cardiovascular system). There are indications that the drug has a bronchodilator effect and at the same time enhances the function of the ciliated epithelium and accelerates the mucociliary transport.
Entitled "Berotek" (Germany), a drug used for the treatment and prevention of asthma, asthma and chronic bronchitis and other bronchopulmonary diseases associated with bronhiolospazmom.
Product: in aerosol containers with a metering valve, spray each time the 0.2 mg dose. Produce one inhalation 2 - 3 times a day. If after the first inhalation effect has not occurred after 5 minutes was repeated inhalation. Following inhalation producing intervals of 5 hours.
Use of the drug can be combined with the use of mucolytics (see. Bromhexine, Lazolvan), xanthine derivatives (see. Theophylline), cromolyn sodium (cm.), Corticosteroids. Bronchodilator action with amplified.
Special formulation fenoterol (Berotec) in combination with holinolitikom ipratropium bromide (Atrovent) is produced in Germany, entitled "Berodual" (cm.) And the formulation containing fenoterol combined with cromolyn sodium, manufactured under the name "Ditek" (see . Kromolinnatry).
Possible side effects of the application of fenoterol: tremor fingers, anxiety, palpitations; sometimes the feeling of tiredness, dizziness, headache, sweating. In these cases, the dose is reduced.
Contraindications - see Izadrin..
Product: in aerosol cans of 15 ml with a metering valve containing 300 unit doses (1 dose contains 0.2 mg of fenoterol hydrobromide).
Storage: at a temperature no higher than 25 'C away from fire and heat sources.
In connection with a relaxing effect on the muscles of the uterus caused by stimulation b 2 adrenoceptor fenoterol found special utility as tocolytic agent and is available for use in obstetric practice called "Partusisten" (see. Drugs affecting the muscles of the uterus).