Medication Description: Dihydroergotoxin (Dihydroergotoxinum)
The dihydrogenated derivative of the amount of alkaloids of the ergotoxin group (ergokristina, ergokornina, ergokriptina), similar in structure and pharmacological properties to dihydroergotamine.
Available in the form of methanesulfonate (mesylate).
Synonyms: Raedergin, Secatoxin, Ergotoxin DG, Alkergot, Circanol, Clavor, DH-Ergotoxin, Erginemin, Ergocomb, Ergodibat, Ergohydrin, Ergoloid mesylat, Ergomed, Ergoxyl, Hyderan, Hydergin, Optamine, Redergin, Ergomed, Ergoxyl, Hyderan, Hydergin, Optamine, Redergin, Ergomed, Ergoxyl Vasolax et al.
For medical use comes in the form of tablets and solutions.
Tablets "Redergin" (Tabulettae "Redergini" 0.0015) contain 0.0015 g (1.5 mg) of dihydroergotoxin methanesulfonate (synonym: Ergoloid mesilate, Ergoloid mesylate).
Prescribed to adults as a vasodilator for disorders of cerebral circulation, with migraine, with the consequences of traumatic brain injury, as well as disorders of peripheral circulation: Buerger's disease, Raynaud's disease, with transient arterial hypertension, circulatory disorders in the retina, with cochleostomyral syndrome. .
Take before meals 1 tablet 3 times a day. Usually take a long time: from 3 - 4 weeks to several months, depending on the severity of the disease, effectiveness, tolerability.
Abroad, dihydroergotoxin methanesulfonate (DH-Еrgotoxin) * is also available in the form of drops for oral administration and solutions for parenteral use.
In hypertension and disorders of the peripheral circulation, start with the appointment of 5 drops of the drug inside 3 times a day, then the dose is increased daily by 2 to 3 drops to receive up to 20-40 drops 3 times a day. The course of treatment for hypertension lasts 3 - 4 months; with spasms of peripheral vessels - 15 - 20 days. In spastic migraines, 5 drops are prescribed 3 times a day in the first days, then the dose is increased to 20-25 drops 3 times a day.
When severe violations of the peripheral circulation are injected intramuscularly, under the skin or intravenously (drip) 1 to 2 ml of injection solution (1 to 2 0.3 mg ampoules).
When endarteritis is sometimes administered intraarterially 1 to 2 ampoules (0.3 0.6 mg) per day. Enter also by electrophoresis (from the positive pole) in 1 - 2 ampoules (0.3 - 0.6 mg) per day.
Method of production: in 1 ml ampoules (0.3 mg) in a package of 50 ampoules; in vials of 50 ml (1 mg in 1 ml).
Storage: List B. In the dark place at a temperature of no higher than + 25 'C.