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Medication Description: Lysuride (Lysuride)

LIZURID *. 3- (9, 10-Didehydro-6-methylergolin-8 a - yl) -1, 1-diethyl urea.

Available in the form of maleate.

Synonyms: Lizenil, Lisenil, Lisenil, Lizenil, Lisuride, Lysenil, Mesorgydin, Prolacam.

Semi-synthetic preparation of ergolinic structure, close to ergot alkaloids (see).

Possesses antiserotoninovy ​​activity.

It is also an agonist of dopamine receptors and in this regard is close to bromocriptine (see), which is also an ergoline derivative.

Used lizurid for the treatment of migraine (mainly for the prevention of seizures). Reduces the frequency and intensity of attacks.

In connection with dopaminergic activity, it is effective to a certain extent in parkinsonism (see. Treatments for Parkinsonism) and, like bromocriptine, is used to treat acromegaly and hyperprolactinemic hypogonadism; inhibits postpartum and pathological lactation.

Assign inside tablets of 0.025 mg. For migraines and allergic diseases, take one tablet 2 to 3 times a day (for migraines, at the first signs of an attack).

When hyperprolactinemia starts with 0.05 mg per day, then increase the dose by 0.05 mg per day every 3 days, bringing to 0.6 mg per day.

When using lizurida can be observed dyspeptic symptoms, drowsiness, tachycardia, lower blood pressure.

The drug does not have a pronounced oxytotic ("uterine") action, however, it is not recommended to prescribe it to pregnant women. It should also not be prescribed to patients with low blood pressure, with disorders of the peripheral circulation, coronary heart disease, and with marked impaired liver and kidney function.

Product form: tablets containing 0.025 mg of lisuride base.

Storage: List B.