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Description of the medicine: Lysuride (Lysuride)

LYSURIDE (Lysuride) *. 3- (9, 10-Didehydro-6-methylergolin-8 a - yl) -1, 1-diethylurea.

Available in the form of maleate.

Synonyms: Lysenil, Lysenil, Lisenil, Lizenil, Lisuride, Lysenil, Mesorgydin, Prolacam.

Semisynthetic preparation of ergoline structure, close to ergot alkaloids (see).

It has antiserotonin activity.

Is also an agonist of dopamine receptors and in this regard is close to bromocriptine (see), which is also an ergoline derivative.

Lizuride is used to treat migraines (mainly for the prevention of seizures). Reduces the frequency and intensity of seizures.

In connection with dopaminergic activity, it is effective to some extent in parkinsonism (see Means for the treatment of parkinsonism) and, like bromocriptine, is used for the treatment of acromegaly and hyperprolactinemic hypogonadism; inhibits postpartum and pathological lactation.

Assign inside tablets of 0.025 mg. For migraines and allergic diseases, take one tablet 2-3 times a day (for migraines, at the first sign of an onset of an attack).

With hyperprolactinemia, start with 0.05 mg per day, then increase the dose by 0.05 mg per day every 3 days, bringing it to 0.6 mg per day.

When using lysuride, dyspeptic symptoms, drowsiness, tachycardia, and a decrease in blood pressure can be observed.

The drug does not have a pronounced oxytocic ("uterine") effect, however, it is not recommended to appoint it to pregnant women. It should also not be prescribed to patients with low blood pressure, with disorders of peripheral circulation, coronary heart disease, with severe violations of the liver and kidneys.

Release form: tablets containing 0,025 mg of lizuride base.

Storage: List B.