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Medication Description: Bupivacaine Hydrochloride (Bupivacaine hydrochloride)

Bupivacaine hydrochloride (Bupivacaine hydrochloride) *.
1-Butyl-2 ', 6'-dimethylphenyl-2-piperidinecarboxamide hydrochloride.

Synonyms: Markain, Carbostesin, Duracain, Marcain, Narcain, Sensorcain, Svedocain.

The chemical structure is close to lidocaine. It is one of the most active and long-acting local anesthetics. It is used for local infiltration anesthesia (0.25%), blockade of peripheral nerves (0.25 - 0.5%), epidural (0.75%) and caudal (0.25 - 0.5%) anesthesia; retrobulbar blockade (0.75%). In obstetric-gynecological practice only 0.25-0.5% solutions are allowed, but not 0.75%. When using a 0.75% solution, caution should be exercised.

When properly used, the drug provides strong and long-lasting anesthesia. If the doses are exceeded, convulsions, depression of the heart activity (up to cardiac arrest) are possible.

Forms of release: in ampoules and vials in the above concentrations, as well as with the addition of epinephrine hydrochloride (1: 200 000).