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Description of the medicine: Methindionum (Methindionum)

Methindionum. 2-Methylamino-2-ethylindanedione-1, 3 hydrochloride.

White or white with a yellowish or pinkish tinge crystalline powder. Easily soluble in water and alcohol.

Methindione is an indanedione derivative. The structure is close to the anticoagulant phenylin (see), but it differs in that it refers to the amino derivatives and does not have an anticoagulant effect. According to its pharmacological properties it is a selectively acting anticonvulsant. Sleeping and sedative does not have.

Applied with large forms of epilepsy with tonic-clonic and psychomotor paroxysms. It is also indicated for depressive, senestopathic and hypochondriacal disorders in patients with epilepsy.

Assign inside after eating adults to 0.25 g per reception. Epilepsy patients with frequent seizures take the drug 6 times a day at intervals of 1, 5 - 2 hours (daily dose of 1, 5 g). With rare seizures, appoint the same single dose of 4 to 5 times a day (daily dose of 1 - 1, 25 g).

If necessary, methindione is combined with phenobarbital, as well as with benzodiazepine drugs (sibazone, nitrazepam).

The transition to methindione treatment, as well as the transition to other antiepileptic drugs, should be gradual, with a consistent reduction in the dose of the previous drug and an increase in the dose of methindione.

For psychopathological disorders in patients with epilepsy, the drug is prescribed 0.25 g 4 times a day.

The drug is usually well tolerated. In some cases, there is dizziness, nausea, tremor in the fingers; In these cases, lower the dose.

The drug is contraindicated in severe anxiety and stress.

Product: tablets of 0.25 g.

Storage: List B. In a dry, sheltered from the world.