Medication Description: De-Nol (De-Nol)
DE-NOL (De-Nol) *.
Bismuth colloidal subcitrate.
Synonyms: Bismuth trikaliya dicitrate, Biscolcitrat, Bismuthate tripotassium dicitrate, De-Noltal, Duosol, Tripotrium dicitrabismutate, Ulceron, etc.
Tribimol (Тtibimol) is close in composition and action to De-nol.
De-nol has an antacid and enveloping effect. When taking the pills inside, it gradually forms a colloidal mass that is distributed over the surface of the gastric mucosa, enveloping the parietal cells; It has not only antacid, but also cytoprotective effect.
Indications for use are the same as for the tablets "Vikalin", "Vikair" and other similar drugs (see Sukralfat, Phosphalugel).
According to the data, de-nol is more effective in the treatment of gastric ulcer and duodenal ulcer than bismuth nitrate, which is associated with its ability to better sanitize the mucous membranes of the stomach and duodenum from pyloric bacteria (Campilo) bacteria. Recently, these pathogens attached great importance in the pathogenesis of peptic ulcer disease.
Assign de-nol 4 times a day: 1 to 2 tablets for 1/2 to 1 hour before breakfast, lunch and dinner, and 1 to 2 tablets before bedtime. The course of treatment 4 to 8 weeks.
Usually the drug is well tolerated; nausea, vomiting are possible. Cal in the treatment of the drug is painted black. It is not recommended to use the drug for severe renal dysfunction.
In order to avoid neurotoxic effects, it is impossible to prescribe the drug for a long time in large doses.
Form release: pills to 0.12 g.