Description medications: Prolonged dosage forms nitroglycerin ()

Prolonged dosage form of nitroglycerin

Prolonged dosage forms nitroglycerin is widely used for chronic forms of coronary heart disease, for the prevention of angina attacks in patients with chronic heart failure.

Tablets or capsules polymeric carriers (with the inclusion of nitroglycerin in microcapsules, granules) are used for oral administration. The effect develops slowly and usually persists for several hours.

On deystviyu6 these drugs mostly similar to each other, and the choice of one or the other is determined by the content of nitroglycerin, some differences in the speed of onset and duration of effect, individual portability.

Domestic drug "Trinitrolong", produced in the form of polymer films, in a room at the mucous membrane gums is long and relatively quickly.

Long-acting formulations for transdermal (cutaneous) application produced in the form of ointments and plasters.

nitrogranulonga Tablets (Tabulettae Nitrogranulongi).

Represents Nitrogranulong micro containing 100 g of nitroglycerin 8 g of ethyl cellulose 24 4 g 40.8 g atsetilftalattsellyulozy and other substances to the total weight of 100 g From microgranules prepared coated tablets (white) with the content in one tablet 0.0029 or 0.0052 g of nitroglycerin (Tabulettae Nitrogranulongi 0,0029 et obductae 0.0052).

Having tablets nitrogranulonga polymeric compounds and a shell covering, creating the conditions for the relatively slow release of nitroglycerin and prolonged action. The drug is intended for oral administration.

Applied to prevent strokes. Take inside before a meal; swallow without chewing, washing down with water. The evolving during the first hour after administration and continuing up to 6 hours or more.

In mild cases, appoint two tablets of 0.0029 g (2, 9 mg) 2 to 3 times during the day; In more severe cases - 1 - 2 tablets of 0.0052 g (5, 2 mg), 2 - 3 times per day (no more than 2 tablets per reception and 6 tablets per day).

The maximum single dose of tablets for receiving 2 mg 9 11.6 mg, ie 4 tablets daily dose -.. 12 tablets (34, 8 mg).

Possible side effects and contraindications are the same as for other drugs nitroglycerin (tablets and capsules).

Product: pills to 0.0029 and 0.0052 g (2, 9, 5, 2 mg) in glass jars of 50 pieces.

Storage: List B. In dry, dark place at room temperature.

Trinitrolong (Trinitrolong). Polymer sheets (films) oval, containing 0.001 g (1 mg) nitroglycerin, painted in green, or 0.002 g (2 mg) nitroglycerin, on the one hand painted white and on the other - light green.

Applied as prolonged drug nitroglycerin for the prevention and for the relief of angina attacks.