Description of the medicine: Flunarizin (Flunarizin)
FLUNARIZIN (Flunarizin) *. trans-1- (Cinnamoyl-4- (4, 4) '- difluorobenzhydryl) piperazine hydrochloride.
Synonyms: Sibelium, Amalium, Flufenal, Flugeral, Flunagen, Flunar, Flunarin, Flunarizine hydrochloride, Flurpax, Fluxarten, Nabratin, Niflucan, Nomigrane, Sibelium, Sibelyum, Vasculoflex, Vertix, etc.
Flunarizine differs from cinnarizine in the presence of two fluorine atoms in phenyl nuclei.
Like cinnarizine, flunarizin blocks calcium channels. The drug relaxes smooth muscles; improves cerebral blood circulation and oxygen supply to the brain; reduces vestibular disorders. It has antihistamine activity. It has an anticonvulsant effect and reduces the frequency of seizures in epilepsy.
It is especially effective for dizziness (vertigo) associated with cerebrovascular accidents, vestibular disorders and migraines.
It is well absorbed when taken orally; has a long half-life, which allows you to take it 1 time per day.
For the prevention of migraine, with vertigo, cerebrovascular accidents and vestibular disorders, adults are prescribed 0.01 g (10 mg) per day, children weighing up to 40 kg - 0.005 g (5 mg) per day.
With epilepsy, flunarizine is recommended mainly as an additional tool for resistance to conventional anticonvulsants. Adults are given 0.015 - 0.02 g (15 - 20 mg) per day, and children with body weight up to 40 kg - 0.005 - 0.01 g (5 - 10 mg) per day.
The drug is usually well tolerated. May cause drowsiness, weight gain, extrapyramidal effects (especially in elderly patients with prolonged use).
Due to drowsiness, flunarizin is recommended to be taken at bedtime and use caution when prescribing it to patients whose work requires a quick physical and mental reaction.
Method of release: tablets of 0.005 and 0.01 g (5 and 10 mg); capsules containing 5 mg of flunarizine.
Storage: List B. In the dark place.