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Medication Description: Flunarizin (Flunarizin)

Flunarizin (Flunarizin) *. trans-1- (Zinnamoyl-4- (4, 4) '- difluorobenzhydryl) piperazine hydrochloride.

Synonyms: Sibelium, Amalium, Flufenal, Flugeral, Flunagen, Flunar, Flunarin, Flunarizine hydrochloride, Flurpax, Fluxarten, Nabratin, Niflucan, Nomigrane, Sibelium, Sibelyum, Vasculoflex, Vertix, etc.

Flinnarizine is distinguished from cinnarizine by the presence of two fluorine atoms with phenyl nuclei.

Like cinnarizine, flunarizine blocks calcium channels. The drug relaxes smooth muscles; improves cerebral circulation and oxygen supply to the brain; reduces vestibular disorders. It has antihistamine activity. It has an anticonvulsant effect and reduces the frequency of attacks during epilepsy.

Especially effective for vertigo associated with disorders of cerebral circulation, vestibular disorders and migraines.

Well absorbed when taken orally; has a long half-life, which allows you to take it 1 time per day.

For the prevention of migraine, with vertigo, disorders of cerebral circulation and vestibular disorders, adults are prescribed 0.01 g (10 mg) per day, children with a body weight of up to 40 kg - 0.005 g (5 mg) per day.

For epilepsy, flunarizin is recommended mainly as an additional agent for resistance to conventional anticonvulsants. Adults are given 0.015-0.02 g (15-20 mg) per day, and children weighing up to 40 kg are given 0.005-0.01 g (5-10 mg) per day.

The drug is usually well tolerated. May cause drowsiness, weight gain, extrapyramidal effects (especially in elderly patients with prolonged use).

In connection with drowsiness, flunarizine is recommended to be taken at bedtime and care should be taken when prescribing it to patients whose work requires a quick physical and mental response.

Method of production: tablets of 0.005 and 0.01 g (5 and 10 mg); capsules containing 5 mg of flunarizine.

Storage: List B. In the dark spot.