Description of the medicine: Ammonium chloride (Ammonii chloridum)
AMMONIA CHLORIDE (Ammonii chloridum).
Synonyms: Ammonium chloride, "Ammonium chloride", Acidamon, Ammonium сhloratum, Аmосhlor.
White crystalline, slightly hygroscopic powder; odorless; "cooling" brackish taste; disappears when glowing. Easily soluble in cold water (1: 3), even easier in hot (1: 1, 3).
Ammonium chloride has a diuretic effect; however, the acid-forming agent of ammonium chloride is an effective tool for the correction of alkalosis. Easily absorbed from the gastrointestinal tract, the drug is converted into urea in the liver, and during this reaction HCl: 2NН 4 Cl + Н 2 СО 3 ~ СО (НН 2) 2 + 2НСl + 2Н 2 O is formed. In this regard, 6 ammonium chloride used for metabolic alkalosis, including in cases of hypochloremic alkalosis, accompanied by the action of some diuretics.
The diuretic effect of ammonium chloride is due to the fact that in the process of compensating for acidosis, sodium is mobilized and excreted by the kidneys, retained in the interstitial fluid, at the same time an appropriate amount of water is released.
The diuretic effect of ammonium chloride with repeated use is gradually reduced. After 24 - 48 hours, the sodium excretion in connection with the compensatory reactions of the body begins to decrease, and after 5 - 7 days the diuretic effect stops; further administration of the drug does not cause a diuretic effect.
As a diuretic, ammonium chloride is sometimes prescribed for edema of cardiac origin.
Take orally (after eating) in the form of 2, 5 - 5% aqueous solution or powder in capsules for 3-5 days with a break. The daily dose for adults is 8 to 12 g (in several doses).
Ammonium chloride also has an expectorant effect and is used for bronchitis, pneumonia, etc. It is prescribed for adults by 0.2 - 0.5 g, for children - 0.1 - 0.25 g per reception 3-5 times a day. Take in powder form in capsules or 0.5 - 2.5% solution.
When taking ammonium chloride, stomach irritation, nausea, and vomiting may appear. To reduce dyspeptic phenomena, the drug should be taken after a meal.
The drug should not be prescribed for acute kidney damage due to the possibility of developing uncompensated acidosis.
Release form: powder.
Storage: in well-corked glass jars in a dry place.
Rp .: Sol. Ammonii chloridi 2, 5% 200 ml
DS 4 tablespoons 5 times a day for 3 to 4 days
Rp .: Inf. rad. Althae 6, 0: 180 ml
Ammonii chloridi 3, 0
Sir. Liquiritiae ad 200 ml
M.DS After 3 hours, 1 tablespoon (expectorant)
Rp .: Ammonii chloridi 0.5 (5, 0)
Sir. Liquiritiae 2 ml
Aq. destill. 100 ml