Description of the medicine: Lespenephril (Lespenephril)
The preparation obtained from the stems and leaves of the leguminous plant Lespedesa capitate (Lesredeza saritata).
Contains catechins, acting like vitamin P, flavones and other substances.
Proposed to reduce azotemia in renal failure. The drug increases diuresis, increases the excretion of sodium and, to a lesser extent, potassium, and enhances the excretion of nitrogenous substances in the urine.
Lespenephril is used in acute and chronic (moderate) nephritis, accompanied by hyperazotemia, as well as in extrarenal azotemia.
Inside appoint 1 - 2 teaspoons per day, and in more severe cases - starting with 2 - 3 (up to 6) teaspoons per day. For maintenance therapy, take for a long time 1/2 / 1 teaspoon every other day.
A lyophilized preparation dissolved in the supplied solvent is administered intravenously or intramuscularly - an average of 4 ampoules per day. The drug can be injected into a vein in the form of drip infusions in an isotonic sodium chloride solution.
In relatively mild cases of renal failure, 2-6 ampoules per day are administered for 8-10 days intramuscularly or intravenously. Additionally, the drug is given orally in courses of 2 to 3 weeks. In more severe cases, 5 to 10 ampoules per day are administered intravenously for 8 to 10 days, then administered orally.
In the early stages of chronic renal failure, the drug is prescribed orally (in addition to other treatment methods).
Method of release: alcohol (70% alcohol) tincture (in 120 ml vials) and lyophilized extract for injection (in vials containing 1 tablet of the extract with 1 ampoule with 10 ml of isotonic sodium chloride solution).
A similar domestic preparation, Lespeflan (Lesreflanum), has been developed. A water-alcohol solution of a purified extract from two-color lespedeza - Lesredeza bicolor (Turcz.). The liquid is light brown with an orange tint (to reddish brown) in color, with a specific odor. Indications for use are the same as for lespenephril.
Take orally 5-15 ml (1 teaspoon - 1 tablespoon) 3-4 times a day. The course of treatment is 3 to 4 weeks (up to 6 weeks). The course of treatment can be repeated after a 2 - 3-week break.
The drug is contraindicated in pregnancy.
Release form: in glass bottles of 100 ml (for oral administration).