Description of the medicine: Benzobromarone (Benzobromarone)
BENZOBROMARON (Benzobromarone) *. 3, 5-Dibromo-1-hydroxyphenyl-2-ethyl-3-benzofuranyl ketone.
Synonyms: Desurik, Normurat, Hipurik, Azabromaron, Desuric, Exurate, Hipuric, Hipurik, Maxuric, Minuric, Normurat, Uriconorm, Uricosuric, Urinorm.
Benzobromarone has a strong uricosuric effect. The effect is mainly due to inhibition of the absorption of uric acid in the proximal renal tubules and increased excretion of uric acid by the kidneys. In addition, the drug inhibits enzymes involved in the synthesis of purines.
Under the influence of benzobromarone, the excretion of uric acid through the intestine increases.
They are used for hyperuricemia (arthritis with hyperuricemia, hematological diseases, psoriasis, etc.) and gout.
Assign to adults by mouth during meals, starting from 0.05 g (50 g = 1/2 tablet) 1 time per day, and with insufficient reduction in the content of urate in the blood, 1 tablet per day.
In acute attacks of gout, sometimes prescribed in short courses of 1/2 tablet 3 times a day for 3 days.
The drug is usually well tolerated. In some cases, gastrointestinal upsets (diarrhea), skin allergic reactions are possible. With gout in the first days, joint pain may intensify, in these cases non-steroidal anti-inflammatory drugs are prescribed.
Contraindications: pregnancy, lactation, severe damage to the liver and kidneys. Children should not be prescribed the drug.
During treatment, to prevent the deposition of calculi in the urinary tract, the patient should drink at least 2 liters of fluid per day.
Release form: tablets of 0.1 g in a package of 30 pieces.
Hipuric is available in the form of tablets containing micronized benzobromarone at 0.08 g (80 mg). The number of tablets prescribed is the same as above.