Medication Description: Benzobromarone
BENZOBROMARON (Benzobromarone) *. 3, 5-Dibromo-1-hydroxyphenyl-2-ethyl-3-benzofuranyl ketone.
Synonyms: Desurik, Normurat, Hipurik, Azabromaron, Desuric, Exurate, Hipuric, Hipurik, Maxuric, Minuric, Normurat, Uriconorm, Uricosuric, Urinorm.
Benzobromarone has a strong uricosuric effect. The effect is mainly due to inhibition of the absorption of uric acid in the proximal renal tubules and an increase in the excretion of uric acid by the kidneys. In addition, the drug inhibits the enzymes involved in the synthesis of purines.
Under the influence of benzobromarone, the excretion of uric acid through the intestines is enhanced.
Applied with hyperuricemia (with arthritis with hyperuricemia, hematological diseases, psoriasis, etc.) and gout.
Assign adults inside during meals, starting with 0.05 g (50 g = 1/2 tablet) 1 time per day, and with an insufficient decrease in the content of urates in the blood, 1 tablet per day.
In acute attacks of gout sometimes prescribed in short courses of 1/2 tablet 3 times a day for 3 days.
The drug is usually well tolerated. In some cases, possible gastrointestinal disorders (diarrhea), skin allergic reactions. Gout in the first days may increase pain in the joints, in these cases, nonsteroidal anti-inflammatory drugs are prescribed.
Contraindications: pregnancy, lactation, severe damage to the liver and kidneys. Do not prescribe the drug to children.
During treatment, to prevent the buildup of calculi in the urinary tract, the patient should drink at least 2 liters of fluid per day.
Form release: pills to 0.1 g in a package of 30 pieces.
Khipurik is available in the form of tablets containing micronized benzobromarone 0.08 g (80 mg). The number of prescribed pills is the same as above.